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Plant Alkaloids as Antiplatelet Agent Drugs of the Future ,

Sep 22, 2016 0183 32 Antiplatelet mechanism of plant alkaloids Various mechanisms have been proposed for the antiplatelet activity of different isolated plant-alkaloids Figure Figure1 1 Researchers have proposed that berberine significantly inhibited platelet aggregation by inhibiting synthesis of thromboxane A2 induced by adenine diphosphate, arachidonic acid, ,...

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A Review of Antiplatelet Activity of Traditional Medicinal ,

Thrombotic events mainly occurred by platelet activation and aggregation The vascular occlusion causes serious disease states such as unstable angina, ischemic stroke, and heart attack Due to the pervading of thrombotic diseases, new antiplatelet drugs are necessary for preventing and treating arterial thrombosis without adverse side effects Traditional medicinal ,...

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Medicinal Plants with Antiplatelet Activity

The identification and/or structure modification of the plant constituents and the understanding of their action mechanisms will be helpful in the development of new antiplatelet agents based on medicinal plants which could contribute to the prevention of thromboembolic-related disorders by inhibiting platelet aggregation...

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Comparative study of Antiplatelet Aggregation Activity of ,

Plant extracts having an antiplatelet aggregation activity may be a potential choice for development of anti-inflammatory drugs because of their natural origin The extraction of bioactive compounds being the most crucial step in the commercial development of natural products it is essential to have rapid and efficient phytochemical...

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Inhibitory effect on human platelet aggregation and ,

This is the first experimental study to demonstrate the potent dose-dependent antiplatelet aggregation, anticoagulant and antioxidant activity of C edulis rhizome and its pure compounds, supporting the traditional use of this plant for the treatment of heart diseas The C edulis rhizome is a pot ,...

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ANTIPLATELET AND ANTIHEMOLYTIC ACTIVITIES OF ,

Sep 30, 2020 0183 32 Aggregation of the platelets was induced by using CaCl 2 at a final concentration of 2 μM Platelet aggregation was recorded by increasing the transmittance value of spectrophotometric measurements at 415 nm To determine the in-vitro antiplatelet aggregation property, different concentrations 100, 200, 300, 400 and 500 μg/ml...

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PDF Antiplatelet aggregation and cytotoxic activity of ,

Jun 10, 2015 0183 32 Antiplatelet aggregation and cytotoxic activity of betulinic acid and its acetyl derivative from Melaleuca bracteata June 2015 Journal of ,...

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Coumarins and antiplatelet aggregation constituents from ,

Feb 01, 1996 0183 32 Studies searching for antiplatelet aggregation principles from Formosan plants revealed that the methanol extract of the root of this plant, collected in Lanyu Island, exhibited strong inhibitory activity on platelet aggregation in vitro...

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Frontiers Antiplatelet and Antithrombotic Activity of a ,

Jan 09, 2019 0183 32 In particular, the antiplatelet activities found in traditional plants have received considerable attention because of their safety and wide range of biological activities Hladovec, 1972 The current study demonstrated that HRT treatment clearly elicited antiplatelet and antithrombotic activities in mice...

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Medicinal Herbals with Antiplatelet Properties Benefit in ,

The common name for this plant is ginger, a traditional medicine with a carminative effect This herb has been investigated for its antiplatelet properti An initial study done on aqueous extract of ginger had shown that it inhibits platelet aggregation induced by AA, adenosine diphosphate, and collagen 19...

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Frontiers Plant Alkaloids as Antiplatelet Agent Drugs ,

Sep 22, 2016 0183 32 Several of these isolated compounds exhibited significant antiplatelet inhibition against arachidonic acid-induced aggregation, collagen-induced, and PAF-induced aggregation Chen et al, 2001 Altogether, these findings showed the potential of plant alkaloids as antiplatelet agents or lead compounds...

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Evaluation of the equivalence of different intakes of ,

Dec 06, 2021 0183 32 The water-soluble tomato extract, Fruitflow® is a dietary antiplatelet which can be used to lower platelet aggregability in primary preventative settings We carried out a pilot study to investigate the range of intakes linked to efficacy and to make an initial assessment of variability in response to Fruitflow® Platelet response to adenosine diphosphate ADP agonist and ,...

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